Welcome to the Tissue Development and Engineering Laboratory directed by Dr. Gregory Underhill. Research in the Underhill lab is aimed at understanding the processes that govern tissue development, regeneration, and disease. Our particular focus is on elucidating the role of cellular microenvironments in stem cell differentiation, and identifying how alterations in microenvironmental signals contribute to cancer as well as congenital and degenerative diseases.

Our interdisciplinary efforts span the boundaries of microfabrication, biomaterials, cell and developmental biology, and genomics. Our overall goal is to develop novel cell-based therapeutic approaches for tissue engineering and regenerative medicine.



December 24, 2018

Underhill Lab paper investigating spatial patterning of liver progenitor differentiation accepted for publication in eLIFE. Congrats to all!

July 23, 2018

Underhill Lab paper accepted for publication in Bioconjugate Chemistry. Congrats Stefan, Megan, and Erik!

June 8, 2018

Dr. Underhill gave a talk at the ECI Nanotechnology in Medicine Conference (Albufeira, Portugal).

March 24, 2018

Dr. Underhill gave a talk at the 2018 Regenerative Medicine Workshop (Charleston, South Carolina).

February 9, 2018

The Underhill Lab has been awarded an R01 grant from the NIH (NIDDK). These efforts are in collaboration with the Khetani Lab (UIC), and are focused on studying microenvironments within the liver in fatty liver disease and liver fibrosis.

January 12, 2018

The Underhill Lab and collaborators at Mayo Clinic have been awarded an R21 grant from NIH (National Cancer Institute).